Speaker at the international ESSENCE conference

A theoretical framework for neurodevelopmental disorders

Operationalization and clinical implications

The video below is my presentation at the 2nd International ESSENCE Conference held in Cape Town, South Africa in April 2023.

It presents my etiological framework for autism and other neurodevelopmental disorders. I briefly deduce the model and outline the causative mechanisms and how they interact to cause a behavioral phenotype that may, or may not, be identified as fulfilling diagnostic criteria.

The publication where the framework is presented can be read and downloaded with the following link: https://doi.org/10.3389/fpsyt.2021.767075

The main focus of the presentation is to simplify the framework and explain a few of the more general clinical implications, such as how the model can inform clinical reasoning around individual risk stratification and minimization, how it can increase the efficiency of screening, and how the introduction of a subclinical diagnostic label can give flexibility with regard to clinically relevant behavioral phenotypes.

The conference presentation

Speaker introduction by the Master of Ceremonies

Commentary on presentation by the Master of Ceremonies